Dr. Kaltenboeck’s Vaccine Platform Gives Immune Systems a Boost
Dr. Bernhard Kaltenboeck, a professor in the Department of Pathobiology, along with research associate Erfan Chowdhury and former research associate Yihang Li, have developed a vaccine platform to treat intracellular diseases for which antibodies are ineffective.
When someone receives a vaccine, it usually means they are trying to build up antibodies toward a disease they do not want to get. For centuries, the approach has worked to prevent the spread of, or even eliminate, many diseases. However, antibodies are insufficient in preventing many other diseases.
“Some diseases occur primarily inside cells,” said Kaltenboeck. “Perhaps it’s a virus that harbors inside of cells, or small bacteria that infect cells as opposed to the surface of tissue, or a cancer. Antibodies are ineffective in these situations. What’s needed is a cellular immune response that can remove these diseased cells.”
To learn more, visit our Web site.