Elaine S. Coleman, DVM, PhD

Associate Professor of Veterinary Anatomy and Neuroscience joined the College of Veterinary Medicine in 2001. She received her D.V.M. degree from Ohio State University in 1984. She completed an internship in Small Animal Surgery and Medicine from 1984-1985, and a residency in Small Animal Neurology/Neurosurgery from 1985-1988, both at Auburn University College of Veterinary Medicine. Dr. Coleman received her Ph.D. from Auburn University in 1992 and was a postdoctoral fellow in the laboratory of Dr. Marie Wooten, Auburn University, from 1993-1994.

Research Interests

Research Interests:  Currently studying the effects of metabolic disorders on astrocyte function in the brain. Astrocytes play an important role in normal neuronal homeostasis and function and are instrumental in the pathophysiology of certain neurotoxicities. Astrocytes function in calcium homeostasis and signal transduction, produce growth factors, modulate synaptic activity, serve as important metabolic regulators for normal neuronal function, regulate extracellular ion homeostasis, and maintain extracellular glutamate at appropriate physiological concentrations.  Techniques utilized in the laboratory include protein extraction, western blotting, and immunohistochemistry.

Teaching Responsibilities:  Dr. Coleman lectures and assists in team teaching labs to first year veterinary students and graduate students in Veterinary Anatomy I as well as Veterinary Neuroscience.

Selected Publications

Dennis JC, Coleman ES, Swyers SE, Moody SW, Wright JC, Judd R, Morrison EE. Changes in mitotic rate and GFAP expression in the primary olfactory axis of streptozotocin-induced diabetic rats. J Neurocytology 34:3-10, 2005.

Coleman ES, Judd R, Hoe L, Dennis J, Posner P. Effects of diabetes on astrocyte GFAP and glutamate transporters in the CNS. GLIA 48:166-178, 2004.

Coleman ES. Canine narcolepsy and the role of the nervous system. Compendium on Continuing Education for the Practicing Veterinarian 21:641-650, 1999.

Coleman ES, Sartin JL. Endotoxin stimulates in vitro pituitary growth hormone release in an eicosanoid-dependent manner. Am J Vet Res 57:1662-1667, 1996.

Coleman ES, Wooten MW. Nerve growth factor-induced differentiation of PC12 cells employs the PMA-insensitive protein kinase C-zeta isoform. J Molecular Neurosci 5:1-15, 1994.

Coleman ES, Elsasser TH, Kemppainen RJ, Coleman DA, Sartin JL. The effects of endotoxin on pituitary hormone secretion in sheep. Neuroendocrinology 58:111-122, 1993.

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