Iryna B. Sorokulova, MS, PhD, DSCI

Elaboration of new probiotics and peroral vaccines based on the alive bacterial cultures; new recombinant Bacillus probiotics; systematization and biological specificity of Bacillus, isolated from different habitats; elaboration of new methods for detection of different microorganisms.  Dr. Sorokulova has created several biotechnological products and saw them through all the stages of development from bench top experiments to clinical practice. One of these products – probiotic Biosporin – is approved as a drug in Russia and Ukraine and is now on market in these countries. Another product - recombinant probiotic Subalin - is approved as a drug in Ukraine.

Krumnov AA, Sorokulova IB, Olsen E, Globa L, Barbaree JM, Vodyanoy VJ. Preservation of bacteria in natural polymers. Journal of Microbiological Methods 78(2):189-194, 2009.

Kuzmicheva GA, Jayanna PK, Sorokulova IB, Petrenko VA. Diversity and censoring of landscape phage libraries. Protein Eng Des Sel 22(1):9-18, 2009.

Kuzmicheva GA, Sorokulova IB, Jayanna PK, Petrenko VA. Landscape phage libraries as a source of bioselective nanomaterials. Nanotech 2:446-448, 2008.

Sorokulova IB, Krumnow AA, Suram P, Mandell AJ, Vodyanoy V. Novel methods for storage stability and release of Bacillus spores. Boitechnology Progress 24(5):1147-1153, 2008.

Guntupalli R, Sorokulova I, Krumnow A, Pustovyy O, Olsen E, Vodyanoy V. Real-time optical detection of methicillin-resistant Staphylococcus aureus using lytic phage probes. Biosens Bioelectron 24(1):151-154, 2008.

Sorokulova IB, Pinchuk IV, Denayrolles M, Osipova IG, Huang JM, Cutting SM, Urdaci MC. The safety of two Bacillus probiotic strains for human use. Dig Dis Sci 53(4):954-963, 2008.

Sorokulova I. (2008) Preclinical Testing in the Development of Probiotics: A Regulatory Perspective with Bacillus Strains as an Example. Clinical Infectious Diseases, 46 (Suppl. 2), S92-S96

Olsen EV, Sykora JC, Sorokulova IB, Chen I-H, Neely WC, Barbaree JM, Petrenko VA, Vodyanoy VJ. Phage fusion proteins as bioselective receptors for piezoelectric sensors. ECS Transactions 2(19):9-25, 2007.  

Nanduri V, Sorokulova IB, Samoylov AM, Simonian AL, Petrenko VA, Vodyanoy V. Phage as a molecular recognition element in biosensors immobilized by physical adsorption. Biosens Bioelectron 22(6):986-992, 2007. 

Balasubramanian S, Sorokulova IB, Vodyanoy VJ, Simonian AL. Lytic phage as a specific and selective probe for detection of Staphylococcus aureus-A surface plasmon resonance spectroscopic study. Biosens Bioelectron 22(6):948-955, 2007.