Wang ZQ and Tao Y-X, 2013. Functions of the third intracellular loop of the human melanocortin-3 receptor. Curr Pharm Des (in press).
Wei HK, Zhou YF, Jiang SZ, Tao Y-X, Sun HQ, Peng J and Jiang SW, 2013. DHA-enriched diet increases skeletal muscle protein synthesis in growing pigs: Association with increased skeletal muscle insulin action and IGF-1 expression. Brit J Nutri (in press).
Tao Y-X, Yuan ZH and Xie J. G protein-coupled receptors as regulators of energy homeostasis. Prog Mol Biol Transi Sci 114:1-43, 2013.
Mo XL, Wei HK, Peng J and Tao Y-X. Free fatty acid receptor GPR120 and pathogenesis of obesity and type 2 diabetes mellitus. Prog Mol Biol Transi Sci 114:251-276, 2013.
Huang H and Tao Y-X. Pleiotropic functions of the transmembrane domain 6 of human melanocortin-4 receptor. J Mol Endocrinol 49:237-248, 2012.
Mo XL, Yang R and Tao Y-X. Functions of transmembrane domain 3 of human melanocortin-4 receptor. J Mol Endocrinol 49:221-235, 2012.
Hafiz S, Dennis J, Schwartz D, Judd R, Tao Y-X, Khazal K, Akingbemi B, Mo XL, Abdel-Mageed AB, Morrison EE and Mansour M. Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation. Int J Oncol 41:1373-1380, 2012.
Yang F and Tao Y-X. Functional characterization of nine novel naturally occurring mutations in human melanocortin-3 receptor. Biochim Biophys Acta – Molecular Basis of Disease 1822:1752-1761, 2012.
Bhushan S, Kondo K, Predmore BL, Zlatopolsky M, King AL, Pearce C, Huang H, Tao Y-X, Condit ME and Lefer DJ. Selective ß2-adrenoreceptor stimulation attenuates myocardial cell death and preserves cardiac function following ischemia-reperfusion injury. Arterioscler Thromb Vasc Biol 32:1865-1874, 2012.
Wang ZQ and Tao YX. Functional studies on twenty novel naturally occurring melanocortin-4 receptor mutations. Biochim. Biophys. Acta 1812:1190-1199, 2011.
Yan J and Tao Y-X. Pharmacological characterization of canine melancortin-4 receptor and its natural variant V213F. Domest Anim Endocrinol 41:91-97, 2011.
Tao YX. Mutations in the melanocortin-3 receptor (MC3R) gene: Impact on human obesity or adiposity. Curr Opin Invest Drugs 11:1092-1096, 2010.
Tao Y-X, Huang H, Wang Z-Q, Yang F, Williams JN, Nikiforovich GV. Constitutive activity of neural melanocortin receptors. Methods Enzymol 484:267-279, 2010.
Tao YX. The melanocortin-4 receptor: Physiology, pharmacology and pathophysiology. Endocrine Reviews 31:506-543, 2010.
Mansour M, White D, Wernette C, Dennis J, Tao Y-X, Collins R, Parker L, Morrison E. Pancreatic neuronal melanocortin-4 receptor modulates serum insulin levels independent of leptin receptor. Endocrine 37:220-230, 2010
Fan Z-C, Tao Y-X. Functional characterization and pharmacological rescue of melanocortin-4 receptor mutations identified from obese patients. J Cell Mol Med 13:3268-3282, 2009.
Tao Y-X, Segaloff DL. Follicle stimulating hormone receptor mutations and reproductive disorders. Prog Mol Biol Transl Sci 89:115-131, 2009.
Roth CL, Ludwig M, Woelfle J, Fan Z-C, Brumm H, Biebermann H, Tao Y-X. A novel melanocortin-4 receptor gene mutation in a female patient with severe childhood obesity. Endocrine 36:52-59, 2009.
Tao Y-X. Mutations in melanocortin-4 receptor and human obesity. Prog Mol Biol Transl Sci 88:173-204, 2009.
Hancock KD, Coleman ES, Tao Y-X, Morrison EE, Braden TD, Kemppainen BW, Akingbemi BT. Genistein decreases androgen biosynthesis in rat Leydig cells by interference with luteinizing hormone-dependent signaling. Toxicol Lett 184:169-175, 2009.
Tao Y-X. Constitutive activation of G protein-coupled receptors and diseases: insights into mechanism of activation and therapeutics. Pharmacology and Therapeutics 120:129-148, 2008.
Wang S-X, Fan Z-C, Tao Y-X. Functions of acidic transmembrane residues in human melanocortin-3 receptor binding and activation. Biochem Pharmacol 76:520-530, 2008.
Fan ZC, Sartin JL, Tao YX. Pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs. Domest Anim Endocrinol 34:383-390, 2008.
Fan Z-C, Sartin JL, Tao Y-X. Molecular cloning and pharmacological characterization of porcine melanocortin-3 receptor. J Endocrinol 196:139-148, 2008.
Tao Y-X. Inactivating melanocortin-4 receptor mutations and human obesity. In Obesity and Energy Metabolism: Research and Clinical Applications, Donohoue PA, Editor. Humana Press, Totowa, NJ. Pages 45-58, 2008.
Tao Y-X. Functional characterization of novel melanocortin-3 receptor mutations identified from obese subjects. Biochimica et Biophysica Acta - Molecular Basis of Disease 1772:1167-1174, 2007.
Zhang M, Tao Y-X, Ryan GL, Feng X, Fanelli F, Segaloff DL. Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations. J Biol Chem 282(35):25527-25539, 2007.
Freitas KCM, Ryan G, Brito VN, Tao Y-X, Costa EMF, Mendonca BB, Segaloff D, Latronico AC. Molecular analysis of the neuropeptide Y1 receptor gene in human idiopathic gonadotropin-dependent precocious puberty and isolated hypogonadotropic hypogonadism. Fertility and Sterility 87(3):627-634, 2007.
Tao Y-X. Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications. Pharmacology and Therapeutics 111:949-973, 2006.
Rong R, Tao Y-X, Cheung BMY, Xu A, Cheung GCN, Lam KSL. Identification and functional characterization of three novel human melanocortin-4 receptor gene variants in an obese Chinese population. Clin Endocrinol 65:198-205, 2006.
Tao Y-X, Segaloff DL. Functional analyses of melanocortin-4 receptor mutations identified from patients with binge eating disorder and non-obese or obese subjects. J Clin Endocrinol Metab 90:5632-5638, 2005.
Tao Y-X. Molecular mechanisms of the neural melanocortin receptor dysfunction in severe early-onset obesity. Mol Cell Endocrinol 239:1-14, 2005.
Tao Y-X, Segaloff DL. Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation. J Clin Endocrinol Metab 89:3936-3942, 2004.
Tao Y-X, Johnson NB, Segaloff DL. Constitutive and agonist-dependent self-association of the cell surface human lutropin receptor. J Biol Chem 279:5904-5914, 2004.
Donohoue PA, Tao Y-X, Collins M, Yeo GSH, O’Rahilly S, Segaloff DL. Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female. J Clin Endocrinol Metab 88:5841-5845, 2003.
Tao Y-X, Segaloff DL. Functional characterization of human melanocortin-4 receptor mutations associated with childhood obesity. Endocrinology 144:4544-4551, 2003.
Shinozaki H, Butnev V, Tao Y-X, Ang KL, Conti M, Segaloff DL. Desensitization of Gs-coupled receptor signaling by constitutively active mutants of the human lutropin/choriogonadotropin receptor. J Clin Endocrinol Metab 88:1194-1204, 2003.
Tao Y-X, Mizrachi D, Segaloff DL. Chimeras of the rat and human FSH receptors (FSHRs) identify residues that permit or suppress transmembrane 6 mutation-induced constitutive activation of the FSHR via rearrangements of hydrophobic interactions between helices 6 and 7. Mol Endocrinol 16:1881-1892, 2002.
Tao Y-X, Abell AN, Liu X, Nakamura K, Segaloff DL. Constitutive activation of G protein-coupled receptors as a result of substitution of a conserved leucine residue in transmembrane helix III. Mol Endocrinol 14:1272-1282, 2000.