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Vitaly J. Vodyanoy, MS, PhD

Professor of Physiology and Director of Biosensor Laboratory, joined the College of Veterinary Medicine in 1989. Dr. Vodyanoy received his M.S. in Physics from Moscow Physical Engineering Institute in 1964, and his Ph.D. in biophysics in 1973 from Agrophysical Research Institute, Leningrad, USSR. He has been a member of the faculty in the Institute of Semiconductors and A.F. Loffe Physicotechnical Institute, Academy of Sciences, Leningrad, USSR. He had worked at the Department of Chemistry, New York University and the Department of Physiology and Biophysics, College of Medicine, University of California, Irvine.

207 Greene Hall
334-844-5405
vodyavi@auburn.edu

Research Interests

Sensory physiology, biophysics of odor detection, receptors, reconstitution of membrane associated macromolecules. The major research aims are to determine the initial chemoreceptive events in the animal olfactory system and to find out how is odorant information translated into electrical events in the olfactory receptor. The work involves the transfer of macromolecules from olfactory receptor cells into artificial bimolecular membranes, monolayer and multilayers, and studying the electrical and chemical properties of the reconstituted systems.

Another focus of this research is the use of functional reconstitution of the olfactory receptor cell to produce an artificial system responsive to small (subnanomolar) concentrations of odorant. The objective of this study is to develop a working prototype of an electrochemical sensor which shares basic molecular mechanisms associated with the initial steps in olfaction. We are also studying glutamate receptors reconstituted in bilayers using a combination of patch clamp and biochemical techniques. The main focus of this work is to determine molecular mechanisms of the specific facilitation of electrical activity of some of these receptors involved in the information storage (memory) in the brain.

Selected Publications

Krumnov AA, Sorokulova IB, Olsen E, Globa L, Barbaree JM, Vodyanoy VJ. Preservation of bacteria in natural polymers. Journal of Microbiological Methods 78(2):189-194, 2009.

Sorokulova IB, Krumnow AA, Suram P, Mandell AJ, Vodyanoy V. Novel methods for storage stability and release of Bacillus spores. Boitechnology Progress 24(5):1147-1153, 2008.

Guntupalli R, Sorokulova I, Krumnow A, Pustovyy O, Olsen E, Vodyanoy V. Real-time optical detection of methicillin-resistant Staphylococcus aureus using lytic phage probes. Biosens Bioelectron 24(1):151-154, 2008.

Olsen EV, Sykora JC, Sorokulova IB, Chen I-H, Neely WC, Barbaree JM, Petrenko VA, Vodyanoy VJ. Phage fusion proteins as bioselective receptors for piezoelectric sensors. ECS Transactions 2(19):9-25, 2007.  

Nanduri V, Sorokulova IB, Samoylov AM, Simonian AL, Petrenko VA, Vodyanoy V. Phage as a molecular recognition element in biosensors immobilized by physical adsorption. Biosens Bioelectron 22(6):986-992, 2007. 

Balasubramanian S, Sorokulova IB, Vodyanoy VJ, Simonian AL. Lytic phage as a specific and selective probe for detection of Staphylococcus aureus-A surface plasmon resonance spectroscopic study. Biosens Bioelectron 22(6):948-955, 2007.

Samoylov AM, Samoylova TI, Pustovyy OM, Samoylov AA, Toivio-Kinnucan MA, Morrison NE, Globa LP, Gale WF, Vodyanoy V. Novel metal clusters isolated form blood are lethal to cancer cells. Cells, Tissues Organs 179(3):115-124, 2005.

Samoylov AM, Samoylova TI, Pustovyy OM, Samoylov AA, Toivio-Kinnucan MA, Morrison NE, Globa LP, Gale WF, Vodyanoy V. Anti-tumor extracts isolated from shark tissue. Molecular Biology of the Cell 15:253A-253A 1398 Suppl. S, 2004.

Sykora JC, Neely WC, Vodyanoy V. Thermodynamic characteristics of mixed monolayers of Amphotericin B and cholesterol. Journal of Colloid and Interface Science 276(1):60-67, 2004.

Josephson EM, Yilma S, Vodyanoy V, Morrison EE. Structure and function of long-lived olfactory organotypic cultures from postnatal mice. Journal of Neuroscience Research 75(5):642-653, 2004.

Sykora JC, Neely WC, Vodyanoy V. Solvent effects on Amphotericin B monolayers. Journal of Colloid and Interface Science 269(2):499-502, 2004.

Olsen EV, Pathirana ST, Samoylov AM, Barbaree JM, Chin BA, Neely WC, Vodyanoy V. Specific and selective biosensor for Salmonella and their detection in the environment. The Journal of Microbiological Methods 53(2):273-285, 2003.

Sykora J, Yilma S, Neely WC, Vodyanoy V. Amphotericin B and cholesterol in monolayers and bilayers. Longmuir 19:858-864, 2003.

Petrenko VA, Vodyanoy VJ. Phage display for detection of biological threat agents. The Journal of Microbiological Methods 53:253-262, 2003.

For a complete list of publications, visit https://fp.auburn.edu/vetmed/vvgroup/vv/articles.aspx

© 2009 Auburn University College of Veterinary Medicine