Dr. Cox is a veterinary neuropathologist studying the pathologic changes in diseases of the central nervous system of cats and dogs. An interdisciplinary research group led by Center Scientists identifies and characterizes genetic abnormalities of cats that result in neurologic diseases, primarily focusing on lysosomal storage diseases. These diseases in the cat are almost identical models of similar diseases in human patients so that findings from research are not only important in veterinary medicine, but also are important for developing therapies for human patients. A second area of research interest is in targeted therapies for disease. Dr. Cox has teamed with Dr. Tatiana Samoylova to use phage display technology to select peptides which can be used to target particular populations of cells such as cancer cells. Both the phage bearing the targeting peptide and the peptide itself have potential for the development of diagnostic and therapeutic reagents. Drs. Cox, Samoylova, and Baker have formed interdisciplinary teams with other investigators and commercial entities to develop contraceptives for the control of dog and cat overpopulations.