Robert L. Judd, PhD Associate Professor of Pharmacology joined the College of Veterinary Medicine in 1998. He received his B.A. in Biology from Hendrix College in 1986 and the Ph.D. degree in Pharmacology/Toxicology from Northeast Louisiana University (School of Pharmacy) in 1990. Dr. Judd subsequently pursued postdoctoral studies under Dr. John Miles at the Mayo Clinic, Medical School (Endocrine Research Unit). There he served as a Research Fellow from 1990-1992, and a Senior Research Fellow from 1992-1993.
334-844-5416 juddrob@vetmed.auburn.edu
Research Interests Dr. Judd’s major research interests center around new treatments for type 2 diabetes mellitus (formerly known as non-insulin-dependent diabetes mellitus-NIDDM). In addition, his lab in conducting investigations into the metabolic ameliorations in glucose and fat metabolism which results in the physiological expression of type 2 diabetes. These current investigations are focused on cytokines secreted from adipose tissue (termed "adipokines") and their role on whole body energy metabolism.  Specifically, Dr. Judd's laboratory is focused on the impact of endothelial cell-derived factors (e.g. endothelin-1 and nitric oxide) on adipokine gene expression and secretion.  [Research is or has been supported by the Pharmaceutical Research and Manufacturers of American Foundation (PhRMA), American Association of Colleges of Pharmacy (AACP), American Diabetes Association (Louisiana and Minnesota Affiliates), National Institutes of Health (NIH), Diabetes Trust Foundation, Diabetes Action Research and Education Foundation.] Boshell Diabetes and Metabolic Diseases Research Programs Jim Fyffe Diabetes Research Fund Selected Publications Bedi D, Clarke KJ, Dennis JC, Zhong Q, Brunson BL, Morrison EE, and Judd RL.  (2006)  Endothelin-1 inhibits adiponectin secretion through a phosphatidylinositol 4,5-bisphosphate/actin-dependent mechanism.  Biochemical and Biophysical Research Communications 345:332-339. Ding Y, Zuo R, Judd RL and Zhong J.  (2006)  Effects of gender differences on cardiac myocyte dysfunction in streptozotocin-induced diabetic rats.  Endocrinology 29(1):135-141. Ding Y, Zuo R, Judd RL, Schwartz DD and Zhong J.  (2005)  Contribution of endothelin-1 in cardiac myocyte dysfunction in type 1 diabetic rats.  J Card-Renal Res 1:23-32. Dennis JC, Coleman ES, Swyers SE, Moody SW, Wright JC, Judd RL and Morrison EE.  (2005)  Changes in mitotic rate and GFAP expression in the primary olfactory acis of Streptozotocin-induced diabetic rats.  J Neurocytology 34:3-10. Coleman ES, Judd RL, Hoe LL, Dennis JC and Posner PP.  (2004)  Effects of diabetes mellitus on astrocyte GFAP and glutamate transporters in the CNS. Glia 48:166-178. Clarke KJ, Zhong Q, Schwartz DD, Coleman ES, Kemppainen RJ and Judd RL.  (2003)  Regulation of adiponectin secretion by endothelin-1. Biochemical and Biophysical Research Communications 312:945-949. Zhong Q, Lin CY, Clarke KJ, Kemppainen RJ, Schwartz DD and Judd RL.  (2002)  Endothelin-1 inhibits resistin secretion in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications 296:383-387. Lin CY, Higginbotham DH, Judd RL, and White BD.  (2002) Central leptin increases insulin sensitivity and normalizes blood glucose concentrations in streptozotocin-treated diabetic rats.  American Journal of Physiology-Endocrinol Metab 282:E1084-E1091. Raman P and Judd RL.  (2000)  Role of glucose and insulin in thiazolidinedione-induced alterations in hepatic gluconeogenesis. European Journal of Pharmacology 409(1):19-29. Judd RL.  (1999)  KRH-594-A Review.  Cardiovascular, Pulmonary and Renal Investigational Drugs 1(3):412-415. Coppack SW, Perrson M, Judd RL and Miles JM. (1999) Glycerol and non-esterified fatty acid metabolism in human muscle and adipose tissue in vivo. American Journal of Physiology 276(39):E233-E240. Diabetes Links American Diabetes Association Diabetes Research Fund Created in Honor of Jim Fyffe Juvenile Diabetes Foundation International National Institute of Health National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)