P. aeruginosa infections typically are contracted from heavily infestated surfaces such as tubing or water tubs, and virtually any animal can contract these opportunistic infections. Depending on the site of infection, clinical symptoms typically appear as localized purulent inflammation. Secondarily, these infections may become disseminated via the bloodstream, leading to symptoms of severe or fatal gram-negative septicemia such as disseminated intravascular coagulation. Cystic fibrosis patients frequently suffer from pneumonia caused by P. aeruginosa. Similarly, patients with burn wounds or immunocompromised individuals frequently contract localized or systemic P. aeruginosa infections.