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Project ALIAS

Auburn Laboratory for Imaging Animal Systems (Project ALIAS)

The goal of Project ALIAS is to provide support for Auburn researchers attempting to address complex biology questions using small animal imaging.  Bioluminescence, fluorescence and radiologic imaging modalities are available for use in small animals for the purpose of assessing of various disease progression models (e.g. Atherosclerosis, Diabetes, Infectious Disease and Cancer) and evaluating efficacy of indicated or novel therapies to alter disease progression. 

Services

  • Operating all existing imaging and physiology equipment contained in the center
  • Providing consultation to investigators regarding the design, performance and analysis of animal imaging experiments
  • Ensuring proper maintenance and calibration of the equipment assigned to the laboratory
  • Ensuring that all experiments conducted within the Laboratory are performed according to approved protocols

Equipment

Bioluminescence, fluorescence and X-ray Imaging: Project ALIAS has an IVIS Lumina XR II system.   Camera - The unit contains an integrated Andor Technologies Cooled CCD USB Camera cooled to -90 C to provide sensitivity over long integration times. Fluorescence - Spectral un-mixing uses a combination of 8 narrow bandpass emission filters and software algorithms to reduce auto-fluorescence background, thereby improving resolution. Integrated X-Ray Module - The sensitivity of the camera enables fast anatomical X-ray acquisitions on the average of 10 seconds, limiting the dosage of radiation to the subject less than 3 mGy.

Rates

Fee structures are being established with consultation with university officials and members of the Auburn University Research Initiative in Cancer (AURIC) advisory committee for long-term maintenance of existing equipment and acquisition of new imaging modalities.  Hourly rates have been established at $50 per imaging session for the IVIS Lumina XR (session consist of initialization of the instrument and 30 minutes imaging time) and $10 per scan for the FujiFilms FLA-5100 .  Preliminary feasibility data acquisition requests will be reviewed and granted based on individual consultation with Dr. Panizzi. Please check instrument and room availability through the Project ALIAS  calendar at  http://teamup.com/ks32de2da009b0c93b/ .  

All labs and investigators are required to remember to bring disposable items:  gloves, lab absorbent chucks, disinfectant wipes, black artisan page, and isoflurane to the center prior to their imaging session. 

Contact Us

Project ALIAS is directed by Dr. Peter Panizzi and advised by Dr. Michael Miller. 

Dr. Panizzi is a faculty member in the Harrison School of Pharmacy with an office at 3211-J Walker and can be reached by email at panizzi@auburn.edu or by phone at 334-844-7941.

 
© 2009 Auburn University College of Veterinary Medicine