Kenneth E. Nusbaum

phone: 334-844-2693
email: nusbake@vetmed.auburn.edu

Kenneth E. Nusbaum earned a bachelor's degree in Fisheries Biology from Cornell in 1972 and completed his DVM from Cornell in 1976. For a year, Dr. Nusbaum was the assistant director of the Animal Institute at the Albert Einstein College of Medicine in the Bronx where he supervised a laboratory animal care facility logging 1.5 million animal-days per year. In 1980, he completed an MS in medical bacteriology at the University of Georgia, and was elected to the American College of Veterinary Microbiologists in 1981. He completed his PhD in viral pathogenesis in 1982. Since arriving at Auburn in 1982, Dr. Nusbaum has done research in food animal virology, spent two months working in an Israeli lab in fish immunology, and served as an AVMA Congressional Fellow on the staff of Senator Edward M. Kennedy.
 

Research Interests

Domestication or intensification of cultivation of most species including human beings leads to a great increase of "new" infectious diseases. One of the most consistent agents to appear in species under intense cultivation is the herpesviruses. Research in my lab has been directed toward understanding and control of vertically transmitted herpesviruses of domestic animals using channel catfish virus as a model.

Work is currently directed to locating and understanding the immediate early gene complex with respect to activation and its role in latency. The answers should provide a diagnostic tool to select virus free brood stock for eradication efforts.
 

Selected Publications

Nusbaum KE and Grizzle JM. Adherence of channel catfish virus to sperm and leukocytes. Aquaculture 1987, 65:1-6.

Nusbaum KE and Grizzle JM. Uptake of channel catfish virus by channel catfish and bluegills. American Journal of Veterinary Research 1987, 48:375-377.

Bird RC, Nusbaum KE, Screws EA, Young-White RR, Grizzle JM, Toivio-Kinnucan M. Molecular cloning of fragments of the channel catfish virus (Herpesviridae) genome and expression of the encoded mRNA during infection. American Journal of Veterinary Research 1988, 49:1850-1855.

Awad MA, Nusbaum KE, Brady Y. Preliminary studies on a newly developed subunit vaccine for channel catfish virus disease. Journal of Aquatic Animal Health 1987, 1:233-237.

Silverstein, PS, Bird, RC, van Santen, VL, Nusbaum, KE. Immediate-early transcription from channel catfish virus genome: characterization of two immediate-early transcripts. J Virol 69: 3161-3166, 1995.

Nusbaum, KE, Morrison, EE. Entry of 35S-labelled Edwardsiellaictaluri into channel catfish. J Aquatic Animal Health 7: 146-149, 1996.

Silverstein, PS, van Santen, VL, Bird, RC, and Nusbaum, KE, 1998.  Characterization of Immediate Early and Early Transcripts From Channel Catfish Virus (IHV-1), Journal of Virology 72:  3900-3906.