David A. Stringfellow

 phone: 334-844-2667
email: strinda@vetmed.auburn.edu

 Dr. David A. Stringfellow,  professor of epidemiology and microbiology, earned the DVM degree in 1970 from Cornell University and the MS degree from Auburn University in 1982. Between 1970 and 1977, he gained experience in food animal practice with emphasis on reproduction in dairy cattle. While working for the Pennsylvania and United States Departments of Agriculture from 1977 to 1983, he acquired additional training in the epidemiology of indigenous and foreign diseases of domestic livestock. Subsequently, he joined the faculty at Auburn University and currently holds a dual appointment in the Departments of Pathobiology at the College of Veterinary Medicine and Animal Health Research of the Alabama Agricultural Experiment Station. Dr. Stingfellow's general area of interest is in the epidemiological aspects of advanced reproductive technologies. He is coordinator of a course in applications of advanced reproductive techniques and coeditor of the Manual of the International Embryo Transfer Society (www.iets.org) .
 

Research Interests

Research in my laboratory has focused on assessment of risks for transmission of infectious diseases through the transfer of in vitro or in vivo derived bovine embryos. Recent efforts have dealt specifically with development of methods for insuring the pathogen-free status of bovine embryos and development of techniques and reagents to study the mechanism by which pathogens adhere to the bovine zona pellucida. Associated areas of study have been clinical applications of in vitro fertilization in cattle, resistance or susceptibility of early embryonic cells to infectious disease producing agents, and development of whole embryo or cell culture models for the study of causes of early embryonic death and the pathogenesis of abortifacient agents.
 

Selected Publications

Stringfellow DA, Givens MD.  Preventing disease transmission through transfer of in-vivo-derived bovine embryos.  Livestock Production Science, 2000;62(3):237-252.

Stringfellow DA, Riddell KP, Galik PK, Damiani P, Bishop MD.  Quality controls for bovine viral diarrhea virus-free IVF embryos.  Theriogenology 2000;53:827-839.

Infectious agents in bovine embryo production: hazards and solutions.  Stringfellow DA, Givens MD. Theriogenology 2000;53:85-94.

Givens MD, Stringfellow DA.  Potential of embryo transfer for infectious disease control. In Howard JL, Smith R (eds), Current Therapy in Food Animal Practice IV 1999;592-595.

Givens MD, Galik PK, Riddell KP, Stringfellow DA.  Uterine tubal cells remain uninfected after culture with in vitro-produced embryos exposed to bovine viral diarrhea virus.  Veterinary Microbiology 1999;70:7-20.

Givens MD, Galik PK, Riddell KP, Brock KV, Stringfellow DA.  Quantity and infectivity of embryo-associated bovine viral diarrhea virus and antiviral influence of a blastocyst impede in vitro infection of uterine tubal cells.  Theriogenology 1999;52:887-900.

Trachte E, Stringfellow D, Riddell K, Galik P, Riddell M Jr, Wright J.  Washing and trypsin treatment of in vivo derived bovine embryos exposed to bovine viral diarrhea virus.  Theriogenology 1998;50:717-726.

Stringfellow DA. Recommendations for the sanitary handling of in vivo derived embryos. In: Stringfellow DA, Seidel SM (eds), Manual of the International Embryo Transfer Society. 1998;79-84.

Riddell KP, Stringfellow DA. The use of antibiotics in media for recovery, culture and storage of embryos. In: Stringfellow DA, Seidel SM (eds), Manual of the International Embryo Transfer Society. 1998;85-89.

Stringfellow DA, Riddell KP, Brock KV, Riddell MG, Galik PK, Wright JC, Hasler JF. In vitro fertilization and in vitro culture of bovine embryos in the presence of noncytopathic bovine viral diarrhea virus. Theriogenology 1997;48:171-183.

Stringfellow DA, Wrathall AE. Epidemiological implications of the production and transfer of IVF embryos. Theriogenology 1995;43:89-96.

Zurovac OV, Stringfellow DA, Brock KV, Riddell MG, Wright JC. Noncytopathic bovine viral diarrhea virus in a system for in vitro production of bovine embryos. Theriogenology 1994;41:841-853.

Riddell KP, Stringfellow DA, Gray BW, Riddell MG, Galik PK. Antibiotic treatment of bovine embryos. Journal of Assisted Reproduction and Genetics 1993;10:488-491.

Stringfellow DA, Riddell MG, Riddell KP, Carson RL, Smith RC, Gray BW, Wright JC. Use of in vitro fertilization for production of calves from involuntary cull cows. Journal of Assisted Reproduction and Genetics 1993;10:280-285.

Riddell KP, Stringfellow DA, Gray BW, Riddell MG, Wright JC, Galik PK. Structural and viral association comparisons of bovine zonae pellucidae from follicular oocytes, day-7 embryos, and day-7 degenerated ova. Theriogenology 1993;401281-1291.

Stringfellow DA, Riddell KP, Zurovac O. The potential of infectious disease control in livestock. New Zealand Veterinary Journal 1991;39:8-17.

Thompson MS, Bird RC, Stringfellow DA, Rossi CR, Lauerman LH. Chemically induced viral resistance in single preimplantation bovine embryos. Biochemical and Biophysical Research Communications 1991;175:10-14.
 

Selected Abstracts

Givens MD, Galik PK, Riddell KP, Brock KV, Stringfellow DA. Potential for noncytopathic strains of bovine viral diarrhea virus to associate with IVF embryos and remain infective.  Theriogenology 2000;53:319 abstr.

Riddell KP, Galik PK, Riddell MG, Givens MD, Carson RL, Stringfellow DA.  Monitoring laboratory procedures for clinical bovine IVF.  Theriogenology 2000;53:430 abstr.

Givens MD, Galik PK, Riddell KP, Brock KV, Stringfellow DA.  Bovine viral diarrhea virus associated with IVF embryos does not infect susceptible cells.  Theriogenology 1999;51:271 abstr.

Langston NL, Stringfellow DA, Galik PK, Garrett GE.  Failure to wash bluetongue virus from Bovine IVF embryos.  Theriogenology 1999;51:273 abstr.

Givens MD, Galik PK, Riddell KP, Stringfellow DA. Bovine viral diarrhea virus was not detected in association with virally exposed IVF bovine embryos. Theriogenology 1998;252 abstr.

Riddell MG, Carson RL, Riddell KP, Galik PK, Stringfellow DA. Use of exogenous FSH to increase yield of oocytes collected from aged beef cows; case reports. Theriogenology 1997;47:162, abstr.

Stringfellow JS, Hathcock TL, Riddell KP, Stringfellow DA, Galik PK, Riddell MG, Carson RL. Introduction of Stenotrophomonas maltophilia through semen used for in vitro production of bovine embryos. Theriogenology 1997;47:382, abstr.

Gray BW, Stringfellow DA, Riddell MG, Riddell KP, Wright JC. Use of gonadotropin releasing hormone (GnRH) and prostaglandin F2alpha to synchronize ovulations in superovulated cattle. Theriogenology 1996;45:334, abstr.

Riddell KP, Stringfellow DA, Gray BW, Riddell MG. Effects of antibiotics on developmental capacity of bovine embryos. Theriogenology 1995;43:308, abstr.

Brock KV, Stringfellow DA. Comparative effects of cytopathic and noncytopathic bovine viral diarrhea virus on bovine blastocysts. Theriogenology 1993;39:196, abstr.

Gray BW, Stringfellow DA, Riddell MG, Riddell KP, Davenport G, Wright JC. The effect of treatment with bovine somatotropin (BST) on the superovulatory response of cattle. Theriogenology 1993;39:227, abstr.

Riddell KP, Stringfellow DA, Panangala VS, Scodras JM. Monoclonal antibodies to the bovine zona pellucida. Theriogenology 1992;37:285, abstr.