Research Study Shows Benefit of Dietary Supplement on Heat-Stress Symptoms

According to a new study conducted by College of Veterinary Medicine researchers, EpiCor fermentate, manufactured by Embria Health Sciences, not only helped to significantly reduce the likelihood of damage to gut lining caused by heat stress, but also showed gut health benefits without heat stress. The new study was published in the Journal of Thermal Biology.

Members of the College of Veterinary Medicine’s research team includes, from left, research associate Ludmila Globa, Dr. Iryna Soroulova, research associate Oleg Pustovyy and Dr. Vitaly Vodyanoy.

“This study is the first report about the efficacy of EpiCor in the prevention of heat stress-related complications,” said Dr. Iryna B. Sorokulova, a professor of microbiology in the Department of Anatomy, Physiology and Pharmacology in the College of Veterinary Medicine. “Future directions of this study will help to understand the feasibility of proposed approaches not only in environmental heat stress but also in heat stress related to physical activity.”

In this study conducted by College of Veterinary Medicine faculty, rats were split into two equal groups, EpiCor fed and control. On the last day of the trial, half of each group were heat stressed at 45°C (113°F) for 25 minutes.

The results of the study indicate that EpiCor may maintain gut health by helping to reduce the likelihood of intestinal barrier damage associated with leaky gut as well as the biochemical changes resulting from that damage. Additional biochemical observations in rats fed with EpiCor included a reduction of serum LPS endotoxins, reduced eryptosis, and a decrease in white blood cell count as compared to the control rats.

These beneficial findings and the positive results from two other published in vitro studies on EpiCor’s effects on the gut, help to reconfirm EpiCor’s beneficial impact on the digestive system and the growing link between immune and gut health.

“We know from past published human clinical trials that EpiCor has proven beneficial effects on immune system function by helping it to respond appropriately to challenges. Our newest research on gut health is showing more and more that EpiCor not only strengthens the immune system, but positively affects gut function as well,” commented Larry Robinson, VP of Scientific Affairs at Embria Health Sciences. “We will continue to do research on how EpiCor works in the gut and how that science complements EpiCor’s shown immune benefits.”