Constantinos S. Kyriakis, DVM, PhD

Education

PhD, Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Belgium, Virology and Vaccinology, 2009
DVM, Aristotle University of Thessaloniki, Macedonia, Greece, 2004

Biography

Dr. Kyriakis received his DVM from the Aristotle University of Thessaloniki in Macedonia, Greece in 2004 and his PhD in virology and vaccinology from the Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Belgium in 2009. He returned to Greece, where he completed his obligatory military service as a veterinary microbiologist at the Hellenic Army Biological Research Center and then worked as technical director at the Animal Health Division of Medical Products Ltd in Athens, Greece. Between 2011 and 2013, he was also an adjunct lecturer at the Faculty of Veterinary Medicine at the University of Thessaly, where he taught virology, immunology and viral infectious diseases to veterinary students and was co-PI in an EU-funded research project investigating the epidemiology of influenza in swine following the 2009 H1N1 pandemic.

He moved to the US in 2013, first as a postdoctoral research fellow at Emory University and then as postdoctoral research associate at the University of Georgia, where he worked for the NIH/NIAID Emory-UGA Center of Excellence for Influenza Research and Surveillance (CEIRS). In April 2018, Dr. Kyriakis joined Auburn University as an assistant professor of food animal disease research at the Department of Pathobiology, College of Veterinary Medicine. He is also an affiliated faculty member at the Center for Vaccines and Immunology (CVI) at the University of Georgia.

Research Interests

Viral diseases of food animals, swine and avian influenza viruses and interspecies transmission, novel vaccine technologies, animal models of viral disease pathogenesis and prevention, swine virology and epidemiology

Publications and Links

Kyriakis CS, Zhang M, Wolf S, Jones LP, Shim BS, Chocallo AH, Hanson JM, Jia M, Liu D, Tripp RA. Molecular epidemiology of swine influenza A viruses in the Southeastern United States highlights regional differences in circulating strains. Vet Microbiol. 2017;211:174-179. doi: 10.1016/j.vetmic.2017.10.016. PubMed PMID: 29102115.

Kyriakis CS, Papatsiros VG, Athanasiou LV, Valiakos G, Brown IH, Simon G, Van Reeth K, Tsiodras S, Spyrou V, Billinis C. Serological Evidence of Pandemic H1N1 Influenza Virus Infections in Greek Swine. Zoonoses Public Health. 2016;63(5):370-3. doi: 10.1111/zph.12235. PubMed PMID: 26477456.

Foni E, Chiapponi C, Faccine S, Baioni, Zanni E, Merenda M, Rosignoli C, Kyriakis CS, Luini M, Mandola ML, Bolzoni L, Nigrelli AD. Influenza D in Italy: Towards a better understanding of an emerging viral Infection in swine. Sci Rep. 2017;7(1): 11660. doi: 10.1038/s41598-017-12012-3. PubMed PMID: 28916759.

Kyriakis CS, Billinis C, Papadopoulos E, Vasileiou NG, Athanasiou LV, Fthenakis GC. Bluetongue in small ruminants: An opinionated review, with a brief appraisal of the 2014 outbreak of the disease in Greece and the south-east Europe. Vet Microbiol. 2015;181(1-2):66-74. doi: 10.1016/j.vetmic.2015.08.004. PubMed PMID: 26304745.

Kyriakis CS. Tomorrow’s vector vaccines for small ruminants. Vet Microbiol. 2015;181(1-2):47-52. doi: 10.1016/j.vetmic.2015.08.003. PubMed PMID: 26297534.

Campbell PJ, Kyriakis CS, Marshall N, Suppiah S, Seladi-Schulman J, Danzy S, Lowen AC, Steel J. Residue 41 of the Eurasian avian-like swine influenza a virus matrix protein modulates virion filament length and efficiency of contact transmission. J Virol. 2014;88(13):7569-77. doi: 10.1128/JVI.00119-14. PubMed PMID: 24760887; PMCID: PMC4054412.

Campbell PJ, Danzy S, Kyriakis CS, Deymier MJ, Lowen AC, Steel J. The M segment of the 2009 pandemic influenza virus confers increased neuraminidase activity, filamentous morphology, and efficient contact transmissibility to A/Puerto Rico/8/1934-based reassortant viruses. J Virol. 2014;88(7):3802-14. doi: 10.1128/JVI.03607-13. PubMed PMID: 24429367; PMCID: PMC3993553.

Kyriakis CS, Rose N, Foni E, Maldonado J, Loeffen WL, Madec F, Simon G, Van Reeth K. Influenza A virus infection dynamics in swine farms in Belgium, France, Italy and Spain, 2006-2008. Vet Microbiol. 2013;162(2-4):543-50. doi: 10.1016/j.vetmic.2012.11.014. PubMed PMID: 23201246.

De Vleeschauwer AR, Baras B, Kyriakis CS, Jacob V, Planty C, Giannini SL, Mossman S, Van Reeth K. Efficacy of an AS03A-adjuvanted split H5N1 influenza vaccine against an antigenically distinct low pathogenic H5N1 virus in pigs. Vaccine. 2012;30(37):5557-63. doi: 10.1016/j.vaccine.2012.06.028. PubMed PMID: 22727727.

Kyriakis CS, Brown IH, Foni E, Kuntz-Simon G, Maldonado J, Madec F, Essen SC, Chiapponi C, Van Reeth K. Virological surveillance and preliminary antigenic characterization of influenza viruses in pigs in five European countries from 2006 to 2008. Zoonoses Public Health. 2011;58(2):93-101. doi: 10.1111/j.1863-2378.2009.01301.x. PubMed PMID: 20042068.

Kyriakis CS, Olsen CW, Carman S, Brown IH, Brookes SM, Doorsselaere JV, Reeth KV. Serologic cross-reactivity with pandemic (H1N1) 2009 virus in pigs, Europe. Emerg Infect Dis. 2010;16(1):96-9. doi: 10.3201/eid1601.091190. PubMed PMID: 20031049; PMCID: PMC2874381.

Kyriakis CS, Gramer MR, Barbe F, Van Doorsselaere J, Van Reeth K. Efficacy of commercial swine influenza vaccines against challenge with a recent European H1N1 field isolate. Vet Microbiol. 2010;144(1-2):67-74. doi: 10.1016/j.vetmic.2009.12.039. PubMed PMID: 20116942.

Kyriakis CS, De Vleeschauwer A, Barbe F, Bublot M, Van Reeth K. Safety, immunogenicity and efficacy of poxvirus-based vector vaccines expressing the haemagglutinin gene of a highly pathogenic H5N1 avian influenza virus in pigs. Vaccine. 2009;27(16):2258-64. doi: 10.1016/j.vaccine.2009.02.006. PubMed PMID: 19428840.

Constantinos, Kyriakis PubMed Publications