Anne Wooldridge , DVM, MS, PhD, DACVIM

Professor & Department Head, Equine Internal Medicine

Anne Wooldridge  Photo
Contact
 

334-844-4490
aaw0002@auburn.edu

Department of Clinical Sciences

Auburn University
College of Veterinary Medicine
1130 Wire Road
Auburn, AL 36849

Education

 

PhD, Duke University Medical School, 2005
MS, Louisiana State University
DVM, Texas A&M University, 1997

Biography

 

Dr. Anne Wooldridge received her DVM from Texas A&M University in 1997 (Summa Cum Laude). She completed a rotating internship in large animal medicine and surgery, a residency in large animal internal medicine, and a Master’s degree at Louisiana State University. Her thesis projects investigated the effects of various drugs on smooth and skeletal muscle contractile function in the equine esophagus.

She completed a Ph.D. in the Department of Pharmacology and Cancer Biology at Duke University Medical School in Durham, North Carolina in 2005 and while there, was awarded a National Science Foundation Graduate Research Fellowship during her Ph.D. training at Duke University. Her dissertation research focused on calcium signaling in smooth and skeletal muscle using a transgenic mouse model.

She currently is an Associate Professor in Equine Internal Medicine where she sees clinical cases on the equine internal medicine service, and trains veterinary students, residents and graduate students.

She collaborates extensively with the Department of Chemical Engineering to evaluate the use of vascular progenitor cells and biomaterials for equine regenerative therapies. She also works with other researchers in the Auburn University College of Veterinary Medicine on both equine and small animal-focused projects.

She has authored or co-authored 28 journal articles and more than 45 abstracts. Dr. Wooldridge is board-certified by the American College of Veterinary Internal Medicine.

Research Interests

 

Endocrine and metabolic disease in horses, endocrinopathic laminitis, vascular disease, equine regenerative medicine, equine endothelial progenitor cells, smooth muscle disorders (feline respiratory disease, equine gastrointestinal motility). Her research in horses is primarily focused on vascular and metabolic disease in the horse, with special interests in laminitis and advancement of regenerative therapies in horses.

Publications

 

Salter MM*, Seeto WJ*, DeWitt BB, Hashimi S, Schwartz DD, Lipke EA, Wooldridge AA (corresponding author). Characterization of Endothelial Colony Forming Cells from Peripheral Blood Samples of Adult Horses. Accepted for publication: American Journal of Veterinary Research, September 2014. *These authors contributed equally

Ray Dillon A, Tillson DM, Wooldridge A, Cattley R, Hathcock J, Brawner WR, Cole R, Welles B, Christopherson PW, Lee-Fowler T, Bordelon S, Barney S, Sermersheim M, Garbarino R, Wells SZ, Diffie EB, Schachner ER. Effect of pre-cardiac and adult stages of Dirofilaria immitis in pulmonary disease of cats: CBC, bronchial lavage cytology, serology, radiographs, CT images, bronchial reactivity, and histopathology.Vet Parasitol. 2014 Sep 17. pii: S0304-4017(14)00492-0. doi: 10.1016/j.vetpar.2014.09.007. [Epub ahead of print]

Dillon AR; Tillson DM; Wooldridge A; Cattley R; Brawner B; Cole R; Welles B; Christopherson P; Fowler-Lee T; Bordelon S; Barney S; Wells W; Diffie E; Schachner E. Effects of IV and SC heartworm homogenate from doxycycline treated and untreated donor dogs on bronchial reactivity and lung in cats. In press: Veterinary Parasitology 2014.

Wooldridge AA, Waguespack RW, Schwartz DD, Venugopal CS, Eades SC, Beadle RE. Vasorelaxation response to insulin in laminar vessel rings from healthy, lean horses. Vet J. 2014 Jul 29. pii: S1090-0233(14)00313-X. doi: 10.1016/j.tvjl.2014.07.021. [Epub ahead of print]

Wooldridge, AA. Invited Guest Editorial: Are insulin resistance and sepsis related? Accepted for publication: Equine Vet Educ. July 2014.

Dillon AR, Tillson DM, Hathcock J, Brawner B, Wooldridge A, Cattley R, Welles B, Barney S, Lee-Fowler T, Botzman L, Sermersheim M, Garbarino R. Lung histopathology, radiography, high-resolution computed tomography, and bronchio-alveolar lavage cytology are altered by Toxocara cati infection in cats and is independent of development of adult intestinal parasites. Vet Parasitol. 2013 Apr 15;193(4):413-26.

Wooldridge AA, Edwards HG, Plaisance E, Taylor DR, Applegate R, Zhong Q, Taintor J, Judd RL. High molecular weight adiponectin in horses. Am J Vet Res. 2012 Aug;73(8):1230-40.

Funk RA, Wooldridge AA (corresponding author), Stewart AJ, Kempainnen R, Behrend E, Johnson AK. Seasonal changes in the combined insulin glucose tolerance test in normal aged horses. J Vet Intern Med. 2012 Jul;26(4):1035-41.

Wooldridge AA, Dillon AR, Tillson DM, Zhong Q, Barney SR. Isometric responses of isolated intrapulmonary bronchioles from cats with and without adult heartworm infection. Am J Vet Res. 2012 Mar;73(3):439-46.

*Funk RA, Stewart AJ, Wooldridge AA, Kwessi E, Kemppainen R, Behrend E, Zhong Q, Johnson AK. Seasonal changes in plasma alpha-melanocyte-stimulating hormone and adrenocorticotropic hormone in response to thyrotropin releasing hormone administration in normal aged horses. J Vet Int Med, 2011 May-Jun;25(3):579-85.

Wooldridge AA, Fortner CN, Lontay B, Akimoto T, Neppl RL, Facemire C, Datto MB, Kwon A, McCook E, Li P, Wang S, Thresher RJ, Miller SE, Perriard JC, Gavin TP, Hickner RC, Coffman TM, Somlyo AV, Yan Z, Haystead TA. Deletion of the PKA/PKG target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. J Biol Chem. 2008 283(17): 11850-9.

Wooldridge AA, MacDonald JA, Erdodi F, Ma C, Borman MA, Hartshorne DJ, Haystead TA. Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides. J Biol Chem. 2004 Aug 13;279(33):34496-504.

Wooldridge AA, Eades SC, Hosgood GL, Moore RM. Effects of treatment with oxytocin, xylazine butorphanol, guaifenesin, acepromazine, and detomidine on esophageal manometric pressure in conscious horses. Am J Vet Res. 2002 Dec;63(12):1738-44.

Wooldridge AA, Eades SC, Hosgood GL, Moore RM. In vitro effects of oxytocin, acepromazine, detomidine, xylazine, butorphanol, terbutaline, isoproterenol, and dantrolene on smooth and skeletal muscles of the equine esophagus. Am J Vet Res. 2002 Dec;63(12):1732-7.