Therapeutic Drug Monitoring (TDM) Pricing and Sample Collection Protocols

TDM Pricing Information (PDF)

Anti-epileptics

  • Most tests (except cyclosporine) require 0.5 mL serum or plasma.
  • Transfer separated serum or plasma to a plastic transport tube.
  • Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to the slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may affect a test result and interpretation.
  • Please do not freeze samples.

BND = Before the next dose

Drugs Sample required

(No separator gel)

 Collection time (Post-dose) Day Run Price Method Ship on ice Notes
Peak Trough   Single Peak & Trough      
Bromide 0.5 mL Serum /Plasma BND T, R $55   Gold chloride No

Do not use a gel barrier tube.
Gabapentin 0.5 mL Serum /Plasma 2 hrs BND
Preferred sample if only one is submitted.		 As received $80 $115 Immunoassay No

Do not use a gel barrier tube.
Levetiracetam (Keppra®) 0.5 mL Serum

(NO plasma)

 2 hrs BND
Preferred sample if only one is submitted.		 T, W, R, F $80 $115 Immunoassay No

Do not use a gel barrier tube.

Please draw in a red top tube, allow time to clot, spin down, draw off, and send the serum. Only serum provides the cleanest sample and, therefore, the most accurate results.
Phenobarbital 0.5 mL Serum /Plasma 2 hrs BND
Preferred sample if only one is submitted.		 T, W, R, F $35 $50 Immunoassay No

Do not use a gel barrier tube.

Fasting sample recommended
Phenytoin (Dilantin®) 0.5 mL Serum /Plasma BND Preferred sample if only one is submitted. As received $55 $80 Immunoassay Yes

Do not use a gel barrier tube.

Fasting sample recommended
Valproic acid 0.5 mL Serum /Plasma 2 hrs BND
Preferred sample if only one is submitted.		 As received $55 $80 Immunoassay Yes

Do not use a gel barrier tube.
Zonisamide 0.5 mL Serum /Plasma 2 hrs BND
Preferred sample if only one is submitted.		 T, R $80 $115 Immunoassay No

Do not use a gel barrier tube.

Serum or plasma should be separated from red blood cells as soon as possible. Excessive hemolysis may interfere with the assay.

Immunomodulators

  • Most tests (except cyclosporine) require 0.5 mL serum or plasma.
  • Transfer separated serum or plasma to a plastic transport tube.
  • Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to the slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may affect a test result and interpretation.
  • Please do not freeze samples.

BND = Before the next dose

Drugs Sample required

(No separator gel)

 Collection time (Post-dose) Day Run Price Method Ship on ice Notes
Peak Trough   Single Peak & Trough      
Cyclosporine 0.5 mL EDTA

whole blood (purple top)

 1.5–2 hrs
Preferred sample if only one is submitted.		 BND W, F $75 $115 Immunoassay No

Do not use a gel barrier tube.

Recommend peak & trough the first time to establish a half-life. A level may be too low to detect if a sample is drawn >12 hours post‐dose.
Leflunomide 0.5 mL Serum /Plasma   BND Every other Monday $100 $115 HPLC No

Do not use a gel barrier tube.
Mycophenolate (Mycophenolic acid) 0.5 mL Plasma 1–2 hrs BND W, F $75 $120 Immunoassay Yes

Do not use a gel barrier tube.

Recommend peak & trough the first time to establish a half-life. A level may be too low to detect if a sample is drawn >12 hours post‐dose.

Antimicrobials

  • Most tests (except cyclosporine) require 0.5 mL serum or plasma.
  • Transfer separated serum or plasma to a plastic transport tube.
  • Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to the slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may affect a test result and interpretation.
  • Please do not freeze samples.

BND = Before the next dose

Drugs Sample required

(No separator gel)

 Collection time (Post-dose) Day Run Price Method Ship on ice Notes
Peak Trough   Single Peak & Trough      
Amikacin 0.5 mL Serum /Plasma 1 hr BND (for toxicity)

4-6 hrs (for half-life)		 As received $105 $130 Immunoassay Yes

Do not use a gel barrier tube.

No glass tube
Gentamicin 0.5 mL Serum /Plasma 2 hrs BND As received $50 $75 Immunoassay Yes

Do not use a gel barrier tube.
Vancomycin 0.5 mL Serum /Plasma 2 hrs BND As received $50 $75 Immunoassay Yes

Do not use a gel barrier tube.

Fasting sample recommended

Antifungals

  • Most tests (except cyclosporine) require 0.5 mL serum or plasma.
  • Transfer separated serum or plasma to a plastic transport tube.
  • Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to the slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may affect a test result and interpretation.
  • Please do not freeze samples.

BND = Before the next dose

Drugs Sample required

(No separator gel)

 Collection time (Post-dose) Day Run Price Method Ship on ice Notes
Peak Trough   Single Peak & Trough      
Itraconazole 0.5 mL Serum /Plasma 3-4 hrs BND As received $120 $150 HPLC No

Do not use a gel barrier tube.
Voriconazole 0.5 mL Serum /Plasma 3-4 hrs BND As received $100 $120 HPLC No

Do not use a gel barrier tube.

Others

  • Most tests (except cyclosporine) require 0.5 mL serum or plasma.
  • Transfer separated serum or plasma to a plastic transport tube.
  • Do not use a gel barrier tube. The use of gel-barrier tubes is not recommended due to the slow absorption of the drug by the gel. Depending on the specimen volume and storage times, the decrease in drug level due to absorption may affect a test result and interpretation.
  • Please do not freeze samples.

BND = Before the next dose

Drugs Sample required

(No separator gel)

 Collection time (Post-dose) Day Run Price Method Ship on ice Notes
Peak Trough   Single Peak & Trough      
Digoxin 0.5 mL Serum /Plasma 1.5-2 hrs BND As received $55 $85 Immunoassay Yes

Do not use a gel barrier tube.
Lidocaine 0.5 mL Serum /Plasma 2-4 hrs BND As received $55 $85 Immunoassay Yes

Do not use a gel barrier tube.
Procainamide 0.5 mL Serum /Plasma     As received $55 $85 Immunoassay Yes

Do not use a gel barrier tube.
Theophylline 0.5 mL Serum /Plasma 2 hrs   As received $55 $85 Immunoassay Yes

Do not use a gel barrier tube.

STAT Fee

Non-HPLC $60 (first test) and $30 (subsequent tests)
HPLC $200

Handling Fee

Non-human primate samples $50 per test
Processing fee for paper submission $5 per test